What is Beta Ecdystrorone?
20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. It is therefore one of the most common moulting hormones in insects, crabs, etc. It is also a phytoecdysteroid produced by various plants, including Cyanotis vaga, Ajuga turkestanica and Rhaponticum carthamoides where its purpose is presumably to disrupt the development and reproduction of insect pests. In arthropods, 20-hydroxyecdysone acts through the ecdysone receptor. Although mammals lack this receptor, 20-hydroxyecdysone may affect mammalian (including human) biological systems in vitro, but there is uncertainty whether any in vivo or physiological effects occur. 20-Hydroxyecdysone is an ingredient of some supplements that aim to enhance physical performance. In humans it binds to the estrogen receptor beta (ERβ) protein-coding gene.
20-Hydroxyecdysone and other ecdysteroids are marketed as ingredients in nutritional supplements for various sports, particularly bodybuilding. A comprehensive study, designed to find any strength or athletic improvement from 20-hydroxyecdysone, was published in 2006. The study looked for improvement in actual exercises performed and tested for improvements/increases in chemical indicators such as body composition and free/available testosterone. The results of the 2006 study concluded that using 30 mg per day of 20-hydroxyecdysone administered orally did not significantly affect anabolic or catabolic responses to resistance training, body composition, or training adaptations. However, a number of earlier studies supported the anabolic effects of 20-Hydroxyecdysone. A more recent study conducted in 2019 by a team that included the Department for Molecular and Cellular Sports Medicine at the German Sport University Cologne, found that significantly higher increases in muscle mass were observed in participants dosed with ecdysterone, with significantly more pronounced increases in one-repetition bench press performance. The study was funded by the World Anti-Doping Agency (WADA) and demonstrated a significant dose-responsive anabolic effect of 20-Hydroxyecdysone supplementation on athletes during resistance training. Furthermore, recent studies have elucidated that the mechanism of action of 20-Hydroxyecdysone on human muscle cells is relatively selective activation of the beta form of the estrogen receptor (ERβ), which is known to result in muscle hypertrophy.
Benefits of Beta Ecdystorone
- A Drastic Increase in Lean Body Mass
- Increased Endurance
- Stimulates Metabolism
- Improves Nerve Function and Enhances Erythropoiesis (the development of mature red blood cells (erythrocytes))
- Decreases Blood Sugar
- Reduces Adipose Tissue
- Improves Nearly Every Bodily Function Including Brain and Liver
- It's Safe and Effective for Men, Women, and Even Teenagers
- Prevents the Loss of Muscle Mass while Promoting Growth of Muscle Fibres
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